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Ⅰ型子宫内膜癌患者盆腔淋巴结转移危险因素分析
张庆华;徐文生;蓝喜
0
(广西医科大学第一附属医院)
摘要:
目的:探讨Ⅰ型子宫内膜癌患者盆腔淋巴结转移相关危险因素,为制定合理手术范围提供依据。方法:对136例Ⅰ型子宫内膜癌患者淋巴结转移的危险因素进行分析。单因素采用χ~2检验或Fisher确切概率法。多因素采用Logistic回归模型。结果:136例Ⅰ型子宫内膜癌患者盆腔淋巴结阳性率9.56%(13/136)。单因素分析表明Ⅰ型子宫内膜癌的组织学分级、癌灶直径大小、肌层浸润深度、脉管浸润与淋巴结转移有关(P<0.05); 多因素Logistic回归模型分析显示组织低分化、肌层浸润深度≥1/2、癌灶直径≥2 cm、有脉管浸润是Ⅰ型子宫内膜癌盆腔淋巴结转移的独立危险因素(P<0.05)。结论:Ⅰ型子宫内膜癌患者盆腔淋巴结转移率低。组织低分化、肌层浸润深度≥1/2、癌灶直径≥2 cm、有脉管浸润的Ⅰ型子宫内膜癌患者更易发生盆腔淋巴结转移。
关键词:  子宫内膜癌  淋巴结转移  危险因素
DOI:
基金项目:
Analysis on Related Factors of Pelvic Lymph Node Metastasis in Patients with Type Ⅰ Endometrial Carcinoma
()
Abstract:
Objective:To investigate the high risk factors of pelvic lymph node metastasis in patients with typeⅠendometrial carcinoma in order to provide the basis for making reasonable operation scope.Methods:Risk factors of pelvic lymph node metastasis were analyzed in 136 cases of typeⅠ endometrial carcinoma.Univariate analysis was performed with Chi square test or Fisher’s exact probability method,and multivariate analysis was performed with a logistic regression mode.Results:The positive rate of pelvic lymph nodes in 136 patients with typeⅠ endometrial carcinoma was 9.56%(13/136).Univariate analysis showed that histological grade,size of lesion,depth of myometrial invasion and vascular invasion were related to lymph node metastasis(P<0.05);Multivariate Logistic analysis showed that low differentiation,deep muscular invasion,tumor diameter≥2 cm and LVSI were independent risk factors of pelvic lymph node metastasis in patients with typeⅠ endometrial carcinoma(P<0.05).Conclusions:The rate of pelvic lymph node metastasis is low in typeⅠ endometrial carcinoma.Patients with low differentiation,deep muscular invasion,tumor diameter≥2 cm and LVSI are more likely to occur pelvic lymph node metastasis in typeⅠ endometrial carcinoma
Key words:  Endometrialcarcinoma  Lymphnodemetastasis  Riskfactor  

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